Download e-book for kindle: Cytopathology of Neuroendocrine Neoplasia: Color Atlas and by Sudha R. Kini MD

By Sudha R. Kini MD

ISBN-10: 1451176333

ISBN-13: 9781451176339

Cytopathology of Neuroendocrine Neoplasia: Color Atlas and Text


The neuroendocrine approach is interesting. it truly is an exciting, complicated process. for hundreds of years, it has sustained the curiosity of scientists, who've supplied the group with a wealth of knowledge on neuroendocrine tumors types—history, genetics, scientific presentation, surgical pathology, differential diagnoses…on every thing except cytopathology…until now. 

This special colour atlas fills a long-standing void in neuroendocrine assets. This atlas presents transparent, descriptive details at the cytopathology of neuroendocrine tumor types and differential diagnoses in a single state-of-the-art, entire source. This distinctive atlas is devoted solely to delivering specialist, illustrated insurance of the cytopathology of neuroendocrine tumors.

Inside, the content material addresses the large distribution of the neuroendocrine cells within the physique and the ever present nature in their neoplasms. Readers also will discover unique descriptions of the morphologic spectrum of the neoplasms (including various terminologies), in addition to their immunocytohistochemical houses, linked ultrastructural findings, secretory items, and their organization with many hereditary syndromes.

Put the ability of this atlas to paintings for you!
• distinct assurance of cytomorphology of neuroendocrine neoplasia offers info no longer present in textbooks
• present tumor classifications for every physique system are incorporated as an appendix on the finish of every chapter.
• Over a thousand full-color photos detail quite a number tumor websites and kinds, aiding in refining the differential diagnosis.
• convenient glossary is helping make clear ameliorations in terminology.


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Additional info for Cytopathology of Neuroendocrine Neoplasia: Color Atlas and Text

Example text

A B Fig. 14: Typical Carcinoid Tumor. A, B: FNA of a lung mass. These well-defined syncytial tissue fragments of neoplastic cells that are cuboidal with uniform nuclei containing granular chromatin strongly suggest a carcinoid tumor, but must be differentiated from an adenocarcinoma. (c) 2015 Wolters Kluwer. All Rights Reserved. 38 Section I: Epithelial Type Neuroendocrine Tumors of typical carcinoid tumors in cytologic preparations generally exhibit poorly defined cell borders and insignificant or scant pale cytoplasm in contrast to histologic sections.

Grossly, they range from small to large bulky tumors, extensively replacing the lung parenchyma, often with large areas of necrosis. Peripherally located tumors often lack lymph node metastasis and do not show evidence of systemic spread. The tumor is well circumscribed, nonencapsulated and may be multinodular. The cut surface is yellow-white to tan. Histologically, LCNECs present typical neuroendocrine growth patterns with large nests or well-defined islands of neoplastic cells demonstrating peripheral palisading or trabeculae and rosettes (Fig.

Strikingly uniform, small, round to cuboidal, sometimes plasmacytoid cells with typical salt–pepper chromatin granules are a hallmark of carcinoid tumors (Fig. 3B,C). The nuclear membranes are smooth and regular. Nucleoli are inconspicuous, and nuclear molding, stretch artifacts, karyorrhexis, or mitotic figures are not present. The cells (c) 2015 Wolters Kluwer. All Rights Reserved. Pulmonary Typical Carcinoid Tumors (Neuroendocrine Carcinoma, Grade I, Well-differentiated NEC, Low-grade NEC) Fig.

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Cytopathology of Neuroendocrine Neoplasia: Color Atlas and Text by Sudha R. Kini MD

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