By Charles S. Cleeland, Michael J. Fisch, Adrian J. Dunn
Melanoma Symptom technological know-how is the 1st interdisciplinary compilation of study at the mechanisms underlying the expression of cancer-related signs. It offers options in medical, animal and in vitro learn, study equipment in mind imaging, and statistical-descriptive techniques to figuring out the mechanistic foundation of symptom expression. This quantity additionally presents views from sufferers, govt and undefined. by means of amassing and synthesizing the constructing threads of latest methods to knowing cancer-related signs, the booklet promotes a pioneering framework for merging behavioral and organic disciplines to elucidate mechanisms of symptom evolution, incorporating new applied sciences, checking out novel brokers for symptom keep an eye on, and bettering sufferer functioning and caliber of existence either in the course of and after melanoma remedy. With a professional editorial group led through Charles S. Cleeland, an internationally-recognized chief in melanoma discomfort overview and remedy, this can be crucial examining for surgical, scientific and clinical oncologists, educational researchers, and pharmaceutical businesses constructing new brokers to manage symptom expression
Preface; Foreword; half I. advent: 1. advent to melanoma Symptom technology Charles S. Cleeland, Adrian J. Dunn and Michael J. Fisch; 2. learning the mechanisms underlying the indicators of sufferers with melanoma Adrian J. Dunn; three. Cytokines, affliction habit: a version for melanoma indicators Steven S. Zalcman, Randall T. Woodruff, Ruchika Mohla and Allan Siegal; half II. melanoma Symptom Mechanisms and versions: medical and uncomplicated technology: four. The medical technology of melanoma ache evaluate and administration Russell ok. Portenoy and Victor T. Chang; five. soreness: simple technology: 5a. Mechanisms of disease-related soreness in melanoma: insights from the research of bone tumors Patrick W. Mantyh and Juan Miguel Jimenez Andrade; 5b. Neuropathic discomfort: uncomplicated technology Patrick M. Dougherty and Haijun Zhang; 6. Cognitive disorder: is chemobrain genuine? Christina A. Meyers and Jeffrey S. Wefel; 7. Cognitive impairment: simple technological know-how Perry N. Fuchs, Jessica A. Boyette-Davis and Adrian J. Dunn; eight. melancholy in melanoma: pathophysiology on the mind-body interface Andrew H. Miller, Michael A. Burke and Charles L. Raison; nine. Depressive affliction: simple technological know-how: 9a. Animal types of depressed temper and ailment habit Adrian J. Dunn; 9b. From irritation to disorder and melancholy: the cytokine connection Robert Dantzer and Keith W. Kelly; 10. Cancer-related fatigue: medical technological know-how Xin Shelley Wang; eleven. constructing translational animal versions of cancer-related fatigue Mary W. Meagher; 12. melanoma anorexia/weight loss syndrome Aminah Jatoi and Nisha Lassi; thirteen. urge for food loss/cachexia: easy technological know-how Tristin D. Brisbois-Clarkson, Wendy V. Wismer and Vickie E. Baracos; 14. Sleep and its problems: scientific technological know-how Sofia Ancoli-Israel and Lianqi Liu; 15. Sleep and its issues Mark R. Opp and Luca Imeri; sixteen. Proteins and signs Bang-Ning Lee and James M. Reuben; 17. Genetic methods to treating and fighting indicators in sufferers with melanoma Quiling Shi and Charles S. Cleeland; 18. sensible imaging of signs T. Dorina Papageorgiou, Edward F. Jackson and Javier O. Valenzuela; 19. High-dose remedy and posttransplantation symptom burden: outstanding a stability Sergio A. Giralt and Loretta A. Williams; half III. scientific views in Symptom administration and learn: 20. selling symptom learn in cooperative teams Lynne I. Wagner and David Cella; 21. functional points of symptom administration in sufferers with melanoma Richard T. Lee and Michael J. Fisch; half IV. Symptom size: 22. Symptom size through sufferer file Charles S. Cleeland and Tito R. Mendoza; 23. The economics of cancer-related indicators: valuing supportive care interventions Lesley-Ann Miller and Jane C. Weeks; 24. Longitudinal versions for indicators Diane L. Fairclough; 25. Bayesian adaptive layout: a brand new method of try the effectiveness of symptom-reducing brokers utilizing patient-reported results Valen E. Johnson and Tito R. Mendoza; half V. executive and views: 26. selling melanoma symptom technological know-how learn Ann O'Mara and Maria Sgambati; 27. constructing symptom administration medications Joanna M. Brell and Lori M. Minasian; 28. Cancer-related signs: concerns for attention in drug and healing organic product label claims within the usa Jane A. Scott; 29. Symptom learn: having a look forward Charles S. Cleeland, Adrian J. Dunn and Michael J. Fisch; Index
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Additional resources for Cancer Symptom Science : Measurement, Mechanisms, and Management
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1). As novel molecules are used to target pathways in cancer treatments, the potential for new treatment-related pain syndromes is likely to increase as well. 17 Many areas for further work have already been mentioned. 18 These areas would build on the limited existing evidence base, exploring some of the implications of the scientific advances that have been made in cancer pain assessment. 1. Examples of treatment-related pain syndromes Basic science methodologies Syndrome Newly characterized physiological processes include the concepts of peripheral nociceptor activation and sensitization, central sensitization with or without glial activation, and descending inhibition.
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Cancer Symptom Science : Measurement, Mechanisms, and Management by Charles S. Cleeland, Michael J. Fisch, Adrian J. Dunn