Bone and Cancer by Aaron M. Havens, Yusuke Shiozawa, Russell S. Taichman PDF

By Aaron M. Havens, Yusuke Shiozawa, Russell S. Taichman (auth.), Felix Bronner, Mary C. Farach-Carson (eds.)

ISBN-10: 1848820186

ISBN-13: 9781848820180

ISBN-10: 1848820194

ISBN-13: 9781848820197

Bone and Cancer is the 5th quantity within the sequence Topics in Bone Biology, edited via Felix Bronner and Mary C. Farach-Carson. This identify good points present wisdom on mechanisms of metastasis, the function of the bone microenvironment in melanoma development, how inflammatory cytokines functionality in metastasis and osteolysis, and the function of osteoblasts, hence bringing to the clinician and researcher mobile and molecular findings that impact the quest for medicinal drugs and bring about translational reviews.

Each bankruptcy includes an in depth bibliography that enables readers to profit extra approximately particular points of the bankruptcy subject. Tables, diagrams and figures illustrate and make clear mobile occasions that bring about improvement and development of melanoma in bone. Insights in keeping with mobile and molecular occasions make clear the scientific photo and should bring about translational examine and concentrated remedy. The chapters, authored by means of gurus from through the international, emphasize how present wisdom can result in higher treatement.

Other titles during this series:-

Bone Formation

Bone Resorption

Engineering of useful Skeletal Tissues

Bone and Osteoarthritis

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Additional info for Bone and Cancer

Example text

3 Head and Neck Osteosarcoma About 6–13% of osteosarcomas occur in the head and neck, with the most common site being the mandible, followed by the maxilla and the other bones of the skull [37, 60, 123, 178]. , arising in response to and arising within radiation fields (as in radiation-treated bilateral retinoblastoma patients) or in response to other disease conditions, such as Paget’s disease [183]. Secondary osteosarcomas of the head and neck are aggressive lesions that are clinically similar to osteosarcomas of the long bones.

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Nature Genetics 16: 307–310 Li ZW, Dalton WS (2006) Tumor microenvironment and drug resistance in hematologic malignancies. Blood Review 20:333–342 Liang Z, Wu T, Lou H, Yu X, Taichman RS, Lau SK, Nie S, Umbreit J, Shim H (2004) Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4. Cancer Research 64:4302–4308 Libert F, Parmentier M, Lefort A, Dumont JE, Vassart G (1990) Complete nucleotide-sequence of a putativeG protein coupled receptor – Rdc1. Nucleic Acids Research 18:1917 Libura JD (2002) CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion.

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Bone and Cancer by Aaron M. Havens, Yusuke Shiozawa, Russell S. Taichman (auth.), Felix Bronner, Mary C. Farach-Carson (eds.)


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